Buy 5-Amino-1MQ in Australia

Buy 5-Amino-1MQ in Australia from Macropus Peptides as a 50mg research vial, priced and ready to order. 5-Amino-1MQ, or 5-amino-1-methylquinolinium, is a small molecule rather than a peptide: a membrane-permeable inhibitor of nicotinamide N-methyltransferase, the enzyme that methylates nicotinamide using S-adenosylmethionine. Blocking that enzyme lets laboratories study how it shapes NAD+ salvage and methyl donor supply in fat and liver cell models. Each vial holds the compound as a dry solid, labelled with name, strength, lot number and storage temperature, with a certificate of analysis for every lot. One 50mg vial keeps a long series of enzyme and cell assays on a single lot, and the salt form is confirmed on each certificate. Order online and your parcel ships from our Australian shelves to any address in the country. 5-Amino-1MQ is sold to adults aged 18 and over for in-vitro laboratory research only, not for human or veterinary use.

Compound	5-Amino-1MQ
Amount	50 mg
Form	Lyophilised powder
Category	Metabolic research
Storage	-20 °C, protect from light
Testing	HPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysis	Available for every lot, matched to the lot number on the label

5-Amino-1MQ 50mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Diluent added (mL)

Buy 5-Amino-1MQ Australia: 50mg Research Vial

Macropus Peptides supplies this NNMT inhibitor as a 50mg vial with a listed price, ready to order from Australian stock. It is a quinolinium small molecule rather than a peptide, and it sits with our metabolic compounds because laboratories routinely run it beside metabolic peptides. Every vial is released by lot with a matching certificate of analysis.

5-Amino-1MQ Australia: what the compound is

The compound is 5-amino-1-methylquinolinium, a quinoline ring carrying a methyl group on its nitrogen and an amino group at position five. That methylated nitrogen gives it a permanent positive charge, yet cell-based assays characterised it as able to cross membranes. It came out of structure-activity work on quinolinium analogues designed to sit in the nicotinamide binding pocket of nicotinamide N-methyltransferase, usually shortened to NNMT, and it was one of the more potent and selective members of that series.

Research material is commonly supplied as the iodide salt, with a formula weight near 286, while the bare cation weighs about 159. The certificate for each lot names the salt form, and that figure decides every molar calculation: 50mg of the iodide salt is roughly 175 micromoles of inhibitor.

5-Amino-1MQ NNMT inhibitor: how it works in research

NNMT moves a methyl group from S-adenosylmethionine, the cell's main methyl donor, onto nicotinamide. The products are 1-methylnicotinamide and S-adenosylhomocysteine. The enzyme therefore sits where two pathways meet: it uses up methyl donor capacity, and it takes nicotinamide away from the salvage route that rebuilds NAD+. It is highly expressed in adipose tissue and liver. By inhibiting it, researchers can test how that junction influences cellular NAD+ levels, S-adenosylmethionine availability and downstream methylation in adipocyte and hepatocyte cultures, and compare the effect with supplying the cofactor directly through NAD+. The most direct readout in these cultures is 1-methylnicotinamide itself, the enzyme product that should fall when inhibition works, measured beside NAD+ and S-adenosylmethionine by liquid chromatography and mass spectrometry.

5-Amino-1MQ research: what the published studies show

Interest in the enzyme as a metabolic target grew from a 2014 Nature paper in which antisense knockdown of NNMT in mouse adipose tissue and liver was used to study energy expenditure and NAD+ and methyl donor metabolism. The quinolinium series was then mapped in a 2017 structure-activity paper, in the Journal of Medicinal Chemistry, that measured enzyme inhibition across analogues. A 2018 study in Biochemical Pharmacology examined selectivity, cell permeability and effects in adipocytes and a high-fat diet mouse model. That knockdown work relied on antisense oligonucleotides rather than a chemical inhibitor, which is why the later quinolinium papers mattered: they gave laboratories a small molecule for the same question. No clinical study of the compound has been published, so the whole record remains enzyme, cell and rodent work. All three appear in our 5-Amino-1MQ research studies library.

5-Amino-1MQ vial specifications

Rather than a peptide cake, the vial holds a dry crystalline solid under a crimped cap. The label shows compound, milligram content, lot and storage temperature, and the matching certificate follows when you send that lot. Keep it at -20 °C away from light, and let it reach room temperature before opening so condensation does not settle on the solid.

5-Amino-1MQ price in Australia

The 50mg quinolinium vial carries a published price and leaves from stock. Divide that price by fifty for the cost per milligram. Because inhibition curves and culture treatments use micromolar concentrations, one vial covers a long series of enzyme and cell experiments, which keeps the cost of each run low. The same vial is packed into the starter kit and is one of three compounds in the metabolic trio.

5-Amino-1MQ 50mg: where to buy in Australia

Most laboratories order the 50mg vial. It is priced, orderable today and holds enough for repeated enzyme assays and multi-plate cell work on one lot. As a small, stable solid it keeps well between experiments when stored dry and cold. Stock strengths for this size:

• 2.5 mL: 20 mg per mL
• 5 mL: 10 mg per mL
• 10 mL: 5 mg per mL

If the certificate lists the iodide salt, the 10 mg per mL stock is close to 35 millimolar, so a thousandfold dilution into media lands in the micromolar range that most inhibition curves span. Make one stock and split it into aliquots rather than weighing small portions from the vial, which keeps the concentration uniform from the first plate to the last.

Best place to buy 5-Amino-1MQ Australia

• Sold online at macropuspeptides.com, priced at $119.99
• Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
• A certificate of analysis for every lot, matched to the lot number printed on the label
• Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
• Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
• Payment by PayID or bank transfer, with your order ID as the reference

How to buy 5-Amino-1MQ online

• Put the 50mg vial in the cart
• Choose the quantity your study needs
• Order the solvent or diluent your method names
• Pay after declaring adult age and a research purpose
• Save the lot code and request its certificate

5-Amino-1MQ calculator: solvent volumes for the 50mg vial

Key a solvent volume into the listing's quinolinium calculator to read off the stock concentration in milligram and microgram terms. For the 50mg vial:

• 2.5 mL: 20 mg per mL
• 5 mL: 10 mg per mL
• 10 mL: 5 mg per mL

Divide 50 by the millilitres added for any other volume, and write the salt form beside the result so molar figures stay correct across the study. Where an aqueous stock suits your protocol, bacteriostatic water can join the order, and other diluents are in lab supplies. Anyone wanting everything in one box can take the starter kit, where the 50mg vial arrives beside a small water bottle, syringes and swabs.

Is 5-Amino-1MQ available in Australia

Yes, as a research chemical only. The quinolinium compound is absent from the ARTG and lacks TGA approval; it is never sold for human or animal use, only for in-vitro chemistry and cell work. Chemicals of this kind are scheduled through the Poisons Standard, which is revised periodically, so check today's listing for your organisation.

5-Amino-1MQ for sale Australia wide

Parcels go from Australia to laboratories in every capital and regional university town, with vials packed upright. It is often ordered with SLU-PP-332, another non-peptide metabolic tool, and with MOTS-C; all three come together in the metabolic trio. See the full metabolic research range.

Questions about 5-Amino-1MQ 50mg