For laboratory research use only · Not for human or veterinary use · 18+
Kits, stacks and value packs

Buy the MOTS-C, 5-Amino-1MQ and SLU-PP-332 Metabolic Trio in Australia

MOTS-C, 5-Amino-1MQ and SLU-PP-332 in separate vials · Available to order, dispatched from Australia
$300.99

Buy the metabolic trio in Australia from Macropus Peptides: three separate research vials of MOTS-C, 5-Amino-1MQ and SLU-PP-332 under one price. Each compound reaches cellular energy metabolism from a different direction. MOTS-C is a mitochondria-encoded peptide linked to AMPK signalling, 5-Amino-1MQ is a small molecule that blocks the enzyme NNMT, and SLU-PP-332 is a synthetic activator of the oestrogen-related receptors that switch on oxidative genes. The trio costs less than buying the three priced single vials one at a time, and because nothing is premixed, each compound can be dissolved in its own solvent, run alone as a control or combined. Every vial is sealed, lot-numbered and labelled with strength and storage temperature, with a certificate of analysis on request. Add bacteriostatic water to the order and it ships from local Australian stock nationwide. For in-vitro laboratory research only, by purchasers aged 18 and over.

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Frequently bought together
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
KitMetabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332
Amountstack
FormResearch kit
ContentsMOTS-C, 5-Amino-1MQ and SLU-PP-332 in separate vials
CategoryKits, stacks and value packs
StorageSee label
TestingHPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label

Buy the Metabolic Trio Australia: MOTS-C, 5-Amino-1MQ and SLU-PP-332

Our metabolic trio combines three compounds that metabolic laboratories increasingly study side by side: MOTS-C, 5-Amino-1MQ and SLU-PP-332. They arrive as three sealed vials in one carton, each with its own lot and certificate of analysis. Only one of the three is a peptide; the other two are small molecules, which is exactly why they are kept apart rather than blended.

What is in the metabolic research trio

  • One MOTS-C 10mg vial, lyophilised peptide
  • One 5-Amino-1MQ 50mg vial, powder
  • One SLU-PP-332 5mg vial, powder
  • Three labels with lot and freezer temperature

MOTS-C is a sixteen residue peptide whose code sits in the mitochondrial genome, inside the 12S rRNA gene, rather than in the nucleus. 5-Amino-1MQ is a small methylquinolinium molecule made to inhibit NNMT, the nicotinamide-methylating enzyme that is abundant in fat and liver cells. SLU-PP-332 is a synthetic pan agonist of the oestrogen-related receptor family, covering the alpha, beta and gamma forms, and acts most strongly on alpha. None of the three is an approved medicine.

How the metabolic trio works in research

The three act at separate control points of cellular energy use. MOTS-C is a signalling peptide: cell and mouse models show it switching on AMPK, the energy sensor of the cell, and relocating to the nucleus during metabolic stress, where it alters nuclear gene activity. 5-Amino-1MQ works on a metabolic enzyme. NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide, so blocking it is studied for its effect on NAD+ salvage and methyl-group balance in adipocytes. SLU-PP-332 acts at the level of transcription, switching on ERR-driven programmes for mitochondrial growth and oxidative metabolism in muscle. A model with all three can compare a peptide signal, an enzyme inhibitor and a receptor agonist on one set of readouts.

Metabolic trio research: what the studies show

Cell Metabolism introduced MOTS-C in 2015 and returned to it in 2018 with evidence of nuclear relocation under stress. For NNMT, a 2014 paper in Nature showed that knocking the enzyme down changed energy expenditure in diet-challenged mice, and a 2018 study in Biochemical Pharmacology tested small molecule inhibitors from the quinolinium class in high-fat diet mice. SLU-PP-332 was reported in ACS Chemical Biology in 2023 as a pan-ERR agonist that raised exercise capacity in mice. All of this work is preclinical. Records are in the MOTS-C research studies library.

Metabolic trio specifications and stock

SpecificationDetail
KitMetabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332
Amountstack
FormResearch kit
ContentsMOTS-C, 5-Amino-1MQ and SLU-PP-332 in separate vials
CategoryKits, stacks and value packs
StorageSee label

Three lots means three certificates; request each by the code on its vial. All three powders go straight into minus 20 °C storage on arrival, inside their carton or another dark container, and stay dry until the day they are prepared.

Metabolic trio price against the three single vials

OptionPrice
Metabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332$300.99

The trio's single price is lower than MOTS-C 10mg, 5-Amino-1MQ 50mg and SLU-PP-332 5mg bought as separate singles. No blend of these compounds exists, because their solvents and stabilities differ too much to share a vial. Labs that need more of the mitochondrial peptide alone can compare the three-vial MOTS-C value pack.

MOTS-C 10mg vial in the metabolic trio

Inside the peptide vial are 10 milligrams, identical to the smaller MOTS-C single. Bacteriostatic water dissolves it readily, and 2 mL makes it 5 mg per mL while 1 mL makes it 10.

5-Amino-1MQ 50mg vial in the metabolic trio

The 5-Amino-1MQ vial holds 50 milligrams, matching the 5-Amino-1MQ vial listing. As a water-soluble salt it can be made up in bacteriostatic water: 5 mL gives 10 mg per mL, and 2.5 mL gives 20 mg per mL.

SLU-PP-332 5mg vial in the metabolic trio

The SLU-PP-332 vial holds 5 milligrams, the fill of SLU-PP-332 5mg. It is hydrophobic and does not suit plain water, so read the lot certificate and datasheet for the recommended organic solvent before opening it. A capsule format is also listed as SLU-PP-332 capsules.

Where to buy the metabolic trio in Australia

  • Sold online at macropuspeptides.com, priced at $300.99
  • Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
  • A certificate of analysis for every lot, matched to the lot number printed on the label
  • Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
  • Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
  • Payment by PayID or bank transfer, with your order ID as the reference

How to order the metabolic trio online

  • Choose the metabolic trio
  • Add it to your cart
  • Add bacteriostatic water for two vials
  • Confirm research use and pay
  • Record all three lot codes

Metabolic stack solvents and bac water

Two of the three vials take bacteriostatic water. MOTS-C at 2 mL and 5-Amino-1MQ at 5 mL use 7 mL between them, which a single 10 mL water vial covers with 3 mL to spare. Other volumes follow the same rule of fill over water: the peptide across 4 mL sits at 2.5 mg per mL, and the NNMT inhibitor across 10 mL sits at 5. SLU-PP-332 is prepared separately in the solvent its datasheet names. Date every preparation and hold aqueous stocks at 2 to 8 °C.

Is the metabolic trio legal in Australia

Not one of the trio appears on the ARTG or carries TGA approval, so in Australia these vials go to in-vitro research only, never to human or animal use. The TGA controls scheduling under the Poisons Standard; confirm your organisation's position before ordering.

Metabolic trio for sale Australia wide

Every trio is packed from Australian stock, then carried to Brisbane, Perth and Melbourne, to Adelaide, Canberra and Hobart, to Darwin and to regional labs. A MOTS-C starter kit or 5-Amino-1MQ starter kit suits a single-compound start with syringes and swabs included, and related research compounds such as Retatrutide sit in the metabolic research range.

References

  1. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism. 2015.
  2. The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress. Cell Metabolism. 2018.
  3. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014.
  4. Synthetic ERRalpha/beta/gamma agonist induces an ERRalpha-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chemical Biology. 2023.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

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Metabolic trio MOTS-C + 5-Amino-1MQ + SLU-PP-332$300.99