For laboratory research use only · Not for human or veterinary use · 18+
Longevity and cognitive

Buy SS-31 Peptide in Australia

Lyophilised powder, 10mg vial · Available to order, dispatched from Australia
Choose strength: 10 MG
$89.99

Buy SS-31 in Australia from Macropus Peptides in a priced 10mg vial, with a 50mg vial quoted on request. Also known as elamipretide, it is a four amino acid peptide that concentrates at the inner mitochondrial membrane and binds cardiolipin, which makes it a standard tool in research on respiration, membrane potential and oxidative stress. Each vial holds lyophilised research material, sealed and labelled with compound, fill, lot number and storage temperature, and every lot has a certificate of analysis on request. The 10mg vial covers respirometry runs and cell culture pilots, while the 50mg fill suits longer programmes that must stay on one batch. Order SS-31 online with bacteriostatic water, add NAD+ or MOTS-C for combined mitochondrial designs, and your parcel is dispatched from our Australian shelves to any Australian address. SS-31 is sold to adults for in-vitro laboratory research only and is not for human or veterinary use.

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Frequently bought together
NAD+ 500mg$139.99
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
CompoundSS-31
Amount10 mg
FormLyophilised powder
CategoryLongevity and cognitive
Storage-20 °C, protect from light
TestingHPLC purity and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label
Peptide calculator

SS-31 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Vial content
10 mg
mg per mL5.00
mcg per mL5,000

Buy SS-31 Australia: 10mg and 50mg Research Vials

Macropus Peptides supplies this mitochondria-targeted tetrapeptide in two fills. Its 10mg vial carries a list price today, whereas the 50mg vial is priced by quote. It is one of the best-characterised peptides in mitochondrial research, and we sell it as lyophilised material for laboratory use. Both fills come from the same supply and differ only in quantity and cost per milligram.

What is SS-31 peptide

SS-31 is a synthetic four amino acid peptide with the sequence D-Arg-Dmt-Lys-Phe-NH2, where Dmt stands for 2',6'-dimethyltyrosine and the chain ends in an amide. The D-arginine at the start protects it from enzymes that trim peptides from their ends, and the alternating aromatic and positively charged residues are what let it reach mitochondria. It comes from a series of small peptides introduced in 2004, in a Journal of Biological Chemistry paper, as antioxidants aimed at mitochondria, and in clinical development it carries the non-proprietary name elamipretide.

How SS-31 works in research

Most molecules aimed at mitochondria are lipophilic cations that are drawn in by the membrane voltage. This peptide behaves differently: it enters cells and gathers at the inner mitochondrial membrane without relying on that voltage. There it binds cardiolipin, a lipid found almost only in that membrane, which holds the respiratory chain complexes and cytochrome c in place. When cardiolipin is oxidised or disordered, cytochrome c drifts away from carrying electrons and electron transport becomes less efficient. Binding to cardiolipin is reported to keep the folded inner membrane, the cristae, intact and to preserve cytochrome c function. Researchers therefore use it to study respiration, membrane potential, reactive oxygen species and cristae structure in isolated mitochondria, cultured cells and animal models.

SS-31 research: what the studies show

The founding 2004 paper examined how the peptides enter mitochondria and measured mitochondrial swelling, oxidative cell death and injury in an isolated heart model after blood flow was interrupted and restored. Kidney ischaemia in rats was the model for a 2013 report in JASN, the American Society of Nephrology journal, which added binding assays to examine its interaction with cardiolipin and cytochrome c. A 2014 review in the British Journal of Pharmacology described the cardiolipin mechanism and summarised preclinical and early clinical evaluation. Elamipretide has since been assessed in clinical trials in inherited mitochondrial disease. Each study is summarised in our SS-31 research studies library.

SS-31 vial specifications

SpecificationDetail
CompoundSS-31
Amount10 mg
FormLyophilised powder
CategoryLongevity and cognitive
Storage-20 °C, protect from light

Each crimped vial holds the tetrapeptide as a white freeze-dried solid, its label stating name, fill, lot and freezer setting. We pair that lot with its certificate of analysis whenever you ask. Unopened stock belongs in a dark -20 °C freezer. After reconstitution keep the solution cold, at 2 to 8 °C, and avoid freeze and thaw cycles. Being strongly positively charged, it can cling to plastic and glass at very low working concentrations, so final dilutions behave better in low-binding tubes.

SS-31 price in Australia

StrengthPricePrice per mg
SS-31 10mg$89.99$9.00 per mg
SS-31 50mgPrice to confirm-

Our 10mg mitochondrial peptide vial is sold at a set price in local currency. The 50mg size is quoted individually, with no charge made before you agree to the figure. At five times the content, the larger fill should carry a clearly lower cost per milligram, which matters for long or multi-arm studies.

SS-31 10mg: where to buy in Australia

Most mitochondrial groups start with the priced 10mg vial. It covers respirometry runs, isolated mitochondria experiments and cell culture pilots on a single lot. A 10mg vial taken up in 2 mL holds 5 mg per mL; taken up in 1 mL it holds 10 mg per mL, useful where a stronger stock suits your working dilutions.

SS-31 50mg: bulk fill quoted on request

The 50mg vial is designed for extended programmes and studies with several arms that should all use one batch. Taken up in 5 mL it holds 10 mg per mL; taken up in 10 mL it holds 5 mg per mL, which mirrors the smaller fill in 2 mL. Request a quote and we reply with a price.

Best place to buy SS-31 Australia

  • Priced 10mg vial, with the 50mg fill quoted on request
  • One supply for both fills, each released under its own lot number
  • Certificate of analysis matched to the lot on your label
  • Sent from inside Australia with no customs hold
  • NAD+ and MOTS-C in the same order for combined mitochondrial studies

How to buy SS-31 online

  • Put the 10mg vial in the cart or email for a 50mg quote
  • Set a vial count to match your study arms
  • Put bacteriostatic water in the cart if required
  • Tick the adult research-use box before paying
  • Keep the lot reference with your respirometry data and ask for its certificate

SS-31 calculator: bac water and stock strength by vial

Stock concentration equals milligrams in the vial divided by millilitres of diluent. Taken up in 1 mL, 2 mL or 5 mL, the 10mg fill holds 10, 5 or 2 mg per mL respectively. Taken up in 5 mL or 10 mL, the 50mg fill holds 10 or 5 mg per mL. Pair the peptide with bacteriostatic water 10mL in one order, or see alternatives in our lab supplies range.

Is SS-31 available in Australia

Yes, for research. Elamipretide lacks an ARTG listing, and no TGA approval exists for it, so our supply is confined to in-vitro and laboratory work and excludes people and animals. The TGA can amend Poisons Standard scheduling, so check the entry that governs your organisation before you order.

SS-31 for sale Australia wide

We pack mitochondrial orders in Australia and dispatch them to capital cities and regional centres, from Darwin and Hobart to Toowoomba and Albury. For mitochondrial work it is commonly paired with NAD+ and MOTS-C, a ready SS-31 starter kit is listed too, and Glutathione adds a thiol redox readout. Other ageing research compounds fill out our longevity and cognitive range.

References

  1. Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. Journal of Biological Chemistry. 2004.
  2. The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. Journal of the American Society of Nephrology. 2013.
  3. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. British Journal of Pharmacology. 2014.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

Questions about SS-31

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SS-31 10mg$89.99