Buy PT-141 Peptide in Australia

Buy PT-141 in Australia from Macropus Peptides as a 10mg lyophilised research vial. PT-141, known by the name bremelanotide, is a cyclic seven residue melanocortin peptide that differs from Melanotan II only at its end, a free acid in place of an amide. That change shifts its activity towards the MC4 and MC3 receptors, which are concentrated in the brain, and it is used in receptor binding, cyclic AMP and central melanocortin pathway research. The vial has a fixed price and is ready to order. It is sealed and labelled with compound, strength, lot number and storage temperature, with a certificate of analysis for each lot. Order online with bacteriostatic water and we send it from our Australian shelves to any Australian address. A nasal spray is listed separately. For in-vitro research by adults only, not for human or veterinary use.

Compound	PT-141
Amount	10 mg
Form	Lyophilised powder
Category	Melanocortin research
Storage	-20 °C, protect from light
Testing	HPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysis	Available for every lot, matched to the lot number on the label

PT-141 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Diluent added (mL)

Buy PT-141 Australia: 10mg Vial

Macropus Peptides supplies this melanocortin agonist as a single 10mg freeze-dried vial with a set price, for laboratories in Australia studying central melanocortin receptors. The powder form keeps best in the freezer, and one strength keeps ordering and record keeping simple. The same peptide is also listed ready-mixed as a nasal spray and inside a starter kit with diluent and consumables.

PT-141 Australia: what the peptide is

PT-141 is the development code for bremelanotide, a synthetic cyclic heptapeptide, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It has exactly the ring and amino acids of Melanotan II, but ends in a free carboxylic acid where its parent carries an amide. It emerged from the same line of alpha-MSH analogue research as a deliberate variant of that parent. Its molecular formula is C50H68N14O10, and the loss of the amide gives the chain one more negative charge at neutral pH than the parent, a small difference that measurably changes how it sits in the receptor pocket. Bremelanotide was later approved as a medicine in the United States in 2019. It has no registration in Australia, where our vials are supplied only as research material.

PT-141 peptide: how the MC4R agonist works in research

Like other melanocortin agonists, the peptide activates receptors that couple to Gs protein and raise cyclic AMP. Its profile differs from its parent: activity is concentrated at MC4R and MC3R, the two melanocortin receptors most abundant in the brain, with weaker action at the others. MC4R sits at the centre of hypothalamic melanocortin signalling, a system reviewed in Endocrine Reviews in 2006 for its roles in energy balance and other functions. Researchers use this free-acid analogue to study MC4R and MC3R binding and activation, to compare it directly with the amide parent, and to probe central melanocortin pathways in rodent models. Standard set-ups include displacement of a radiolabelled NDP-MSH tracer from membranes carrying a single receptor subtype, cyclic AMP accumulation in transfected HEK293 cells, and side-by-side runs against SHU9119, the MC3R and MC4R antagonist built on the same cyclic scaffold.

PT-141 research: what the studies show

Its target receptors were among those first cloned in the family described by Science in 1992. The cyclic lactam scaffold it inherits dates from a 1989 Journal of Medicinal Chemistry paper. A 2006 review in Peptides explains how the free-acid form was selected from that series and taken into clinical study, and the same year Endocrine Reviews summarised what was known of melanocortin receptor physiology. Two phase 3 trials, published together in Obstetrics and Gynecology in 2019, supported the United States approval that year. Designs and models for every entry are set out in the PT-141 research studies library.

PT-141 vial specifications

Bremelanotide sits in the vial as a white lyophilised solid of roughly 1,025 g/mol, closed with a stopper and crimp. Its label shows compound, 10mg fill, lot and freezer storage. Protect it from light as well as heat, because the tryptophan in the ring is prone to photo-oxidation. The matching certificate of analysis is released against the lot.

PT-141 price in Australia: one strength, one figure

With one strength there is one Australian dollar price, and a milligram costs a tenth of it however many vials you take. The PT-141 starter kit costs a little more and adds diluent (3 mL), a pack of ten 0.5 mL syringes and twenty swabs, which suits a lab placing its first melanocortin order. When a study compares this peptide with its amide parent, ordering both in one checkout means both arrive and can be reconstituted together.

PT-141 10mg: the vial to order

The 10mg vial is enough for a series of MC4R and MC3R binding or signalling experiments on one lot. Reconstituted in 2 mL, bremelanotide sits at 5 mg/mL; in 4 mL, 2.5 mg/mL. Smaller working solutions are then prepared from that stock. At about 1,025 g/mol, 5 mg/mL is close to 4.9 millimolar, so two thousandfold steps take it from stock to the low nanomolar range used on binding plates. Twenty aliquots of 0.1 mL from a 2 mL stock each hold 0.5mg, which lets one vial cover a month of runs without the stock being warmed repeatedly.

PT-141 vial or nasal spray: the right format to buy

We list the peptide in two formats. The lyophilised vial is for laboratories that prepare their own stock solutions and want dry powder for long frozen storage. The nasal spray is a separate product supplied in solution, 10mg in 10 mL or 1 mg/mL, which is five times weaker than the vial made up with 2 mL, and the starter kit packs the vial with water and consumables.

Where to buy PT-141 in Australia

• Sold online at macropuspeptides.com, priced at $109.99
• Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
• A certificate of analysis for every lot, matched to the lot number printed on the label
• Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
• Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
• Payment by PayID or bank transfer, with your order ID as the reference

How to get PT-141: ordering online

• Choose between the plain 10mg vial and the kit, then set a quantity
• Add Melanotan II if the study compares amide and acid forms
• Include bacteriostatic water for mixing
• Confirm adult research use at checkout
• Write down the lot code when the box arrives; its certificate follows on request

PT-141 calculator: mixing volumes for the 10mg vial

Ten milligrams divided by the chosen volume gives the stock:

• 1 mL: 10 mg/mL
• 2 mL: 5 mg/mL
• 2.5 mL: 4 mg/mL
• 5 mL: 2 mg/mL

The listing calculator converts other volumes into mg/mL and mcg/mL. Order bacteriostatic water 10mL alongside the vial; other consumables sit in lab supplies.

Is PT-141 available in Australia

As a research chemical, yes. No bremelanotide product holds an ARTG entry, so it may not be supplied here for human or veterinary use, and our vials are sold for in-vitro study only. Unregistered peptide scheduling comes from the TGA's Poisons Standard, which is updated regularly, so check its current terms before ordering.

PT-141 for sale Australia wide: parcels to every capital

We dispatch from Australian stock to research addresses in Brisbane, Sydney, Canberra, Melbourne, Hobart, Adelaide, Perth and Darwin, and to regional campuses such as Armidale, Townsville and Wagga Wagga, with no import step to hold a parcel up. Melanotan II, Melanotan 1 and Kisspeptin-10 are listed in the same melanocortin research range.

Questions about PT-141 10mg