Buy Melanotan 1 Peptide in Australia

Buy Melanotan 1 in Australia from Macropus Peptides as a 10mg lyophilised research vial. Melanotan 1, also known as afamelanotide, is a linear 13 amino acid analogue of alpha-melanocyte stimulating hormone with two substitutions that make it far more resistant to enzymes than the natural hormone. It acts mainly at the MC1 melanocortin receptor and is used as a reference agonist in receptor binding, cyclic AMP signalling and melanocyte cell studies. The vial is priced and ready to order. Each one is sealed, labelled with compound, strength, lot number and storage temperature, and backed by a certificate of analysis for its lot. Buy online, add bacteriostatic water if needed, and your parcel is sent from Australia to any address in the country. Supplied to adults for in-vitro laboratory research only, not for human or veterinary use.

Compound	Melanotan 1
Amount	10 mg
Form	Lyophilised powder
Category	Melanocortin research
Storage	-20 °C, protect from light
Testing	HPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysis	Available for every lot, matched to the lot number on the label

Melanotan 1 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Diluent added (mL)

Buy Melanotan 1 Australia: 10mg Vial

Macropus Peptides stocks this melanocortin peptide as one strength, a 10mg lyophilised vial with a fixed price, for Australian laboratories working on receptor pharmacology and pigment cell biology. With a single fill there is no strength to choose: order the number of vials your study needs and keep them on one lot.

Melanotan 1 Australia: what the peptide is

This is the research name for afamelanotide, a synthetic copy of alpha-melanocyte stimulating hormone (alpha-MSH) with two changes. Methionine at position 4 is replaced by norleucine, which removes a residue that oxidises easily, and phenylalanine at position 7 is switched to its D form, which blocks enzymes that break the natural hormone down. The result is a straight-chain peptide of thirteen residues, Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2. It was described in PNAS in 1980 as far more potent and longer acting than alpha-MSH in pigment cell bioassays. Our vials are research material and are not registered for any use.

Melanotan 1 peptide: how the MC1R agonist works in research

Alpha-MSH and its analogues act on the melanocortin receptors, a family of five G protein-coupled receptors named MC1R to MC5R. The analogue binds mainly to MC1R, the receptor on melanocytes that couples to Gs protein and raises cyclic AMP inside the cell, which in turn switches on the enzymes of eumelanin synthesis. Its binding favours MC1R over the other subtypes, which makes it a useful selective reference when laboratories need to separate MC1R signalling from the wider melanocortin system. Typical work includes radioligand binding, cyclic AMP accumulation, melanocyte and melanoma cell line studies, and structure-activity comparisons with cyclic analogues.

Melanotan 1 research: what the published record shows

The analogue's original description appeared in PNAS in 1980, based on frog skin and melanoma bioassays. Genes for the whole melanocortin receptor family were isolated twelve years later and published in Science in 1992. Peptides ran a 2006 historical review charting these analogues from early bioassays into clinical programmes. Afamelanotide went on to human trials, and two phase 3 studies in erythropoietic protoporphyria, a rare light-sensitivity disorder, appeared in NEJM in 2015 measuring tolerated time in sunlight. Every paper is summarised by design and model in the afamelanotide research studies collection.

Melanotan 1 vial specifications and storage

The vial holds a white freeze-dried powder, molecular weight near 1,647 g/mol, closed by a grey stopper and a crimped seal. On the label: compound name, 10mg fill, lot code and storage temperature. The tryptophan at position 9 is light-sensitive, so this vial belongs in its carton in the freezer. Send the lot code to receive its certificate of analysis. The chain carries two basic residues, arginine and lysine, plus histidine, against a single glutamic acid, so it sits on the basic side at neutral pH and dissolves without difficulty in bacteriostatic water.

Melanotan 1 price in Australia: cost per milligram

One list figure applies to the 10mg vial, and it is in stock to order immediately. Per milligram, that works out at one tenth of the vial price. Ordering the full quantity a study needs in one checkout keeps every vial on the same lot and avoids paying for a second parcel later. The Melanotan 1 starter kit is the alternative for a first order: the same vial packed with a 3 mL diluent, ten fine 0.5 mL syringes and a set of alcohol swabs.

Melanotan 1 10mg: the vial to order

The 10mg vial suits a complete MC1R binding or signalling series. Receptor assays typically work at very low concentrations, so one vial reconstituted to a concentrated stock can supply many plates. A 2 mL reconstitution sets the linear analogue at 5 mg/mL, and 5 mL sets it at 2 mg/mL. A single 10mg vial also means fewer lots to track than a run of small fills. In molar terms, at about 1,647 g/mol the 5 mg/mL stock is close to 3.0 millimolar, so a thousandfold dilution gives roughly 3 micromolar, a convenient intermediate for serial dilution into assay buffer.

Melanotan 1 or Melanotan II: which to buy

The two are often confused. The linear analogue is weighted towards MC1R. Melanotan II is a smaller cyclic peptide acting at four of the five subtypes with little preference between them. Laboratories comparing selective and non-selective agonists frequently order both, and PT-141, the free-acid relative of the cyclic peptide, is a third comparator.

Where to buy Melanotan 1 in Australia

• Sold online at macropuspeptides.com, priced at $89.99
• Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
• A certificate of analysis for every lot, matched to the lot number printed on the label
• Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
• Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
• Payment by PayID or bank transfer, with your order ID as the reference

How to get Melanotan 1: ordering online

• Add the 10mg vial, or the starter kit, to your cart
• Set the quantity your assay series needs
• Include bacteriostatic water when the lab is out of it
• Add Melanotan II or PT-141 as a cyclic comparator if useful
• Declare adult research use, pay and note the lot on arrival

Melanotan 1 calculator: water volumes for 10mg

For this single strength the rule is ten divided by the volume in millilitres:

• 1 mL of water: 10 mg/mL
• 2 mL of water: 5 mg/mL
• 4 mL of water: 2.5 mg/mL
• 10 mL of water: 1 mg/mL

The calculator on the listing gives any other volume in mg/mL and mcg/mL. Buy bacteriostatic water 10mL with the vial or see lab supplies; the starter kit bundles the vial with 3 mL of water.

Is Melanotan 1 available in Australia

Only as a research chemical. Our vials carry no ARTG listing and are barred from human or animal use, so they are sold strictly for in-vitro laboratory work. The TGA has published warnings about unapproved melanotan products marketed to the public, and scheduling follows the Poisons Standard, so check its present wording against your organisation's work before ordering.

Melanotan 1 for sale Australia wide: melanocortin parcels nationwide

From Australian stock we dispatch to research addresses in Sydney, Melbourne, Brisbane, Perth, Adelaide, Hobart and Darwin, and to regional towns, and nothing passes through customs. The cyclic comparators Melanotan II and PT-141 can travel in the same box. Kisspeptin-10 and the other receptor ligands in our melanocortin research range can share the parcel.

Questions about Melanotan 1 10mg