For laboratory research use only · Not for human or veterinary use · 18+
Melanocortin research

Buy Melanotan II Nasal Spray in Australia

Nasal spray, 10 mg / 10 ml · Available to order, dispatched from Australia
$89.99

Buy Melanotan II nasal spray in Australia from Macropus Peptides: a 10mL pump bottle containing 10mg of the cyclic melanocortin peptide already in solution, a concentration of 1 mg per mL. Melanotan II is a lactam-bridged analogue of alpha-melanocyte stimulating hormone that binds four of the five melanocortin receptors, which makes it a standard non-selective reference agonist in receptor pharmacology. Because the solution is made up before dispatch, there is no powder to reconstitute and no bacteriostatic water to buy. Each bottle is labelled with compound, amount, volume, concentration and lot number, and a certificate of analysis is available for every lot. The bottle is priced the same as our 10mg vial of dry powder. Order Melanotan II nasal spray online and it ships from our Australian shelves to any address in the country. Sold only for in-vitro laboratory research, to researchers aged 18 and over, and never for human or veterinary use.

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Frequently bought together
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
CompoundMelanotan II nasal spray
Amount10 mg / 10 ml
FormNasal spray bottle, solution
CategoryMelanocortin research
StorageSee label
TestingHPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label

Buy Melanotan II Nasal Spray Australia: 10mg in a 10mL Bottle

Macropus Peptides carries the cyclic melanocortin agonist in two presentations: the familiar 10mg freeze-dried vial, and a 10mL pump bottle in which the same quantity is supplied pre-dissolved. Filling, sealing and lot release happen before the bottle leaves us, so a receptor laboratory receives a working solution rather than a dry cake.

Melanotan II spray: what the peptide is

The compound is a synthetic cyclic analogue of alpha-melanocyte stimulating hormone, the 13-residue hormone behind pigmentation and several other melanocortin signals. It was designed at a university in the United States in the late 1980s as a shorter, sturdier version of that hormone: seven residues closed into a ring by a lactam bridge, with a molecular weight of about 1,024 daltons. The ring holds the active shape and protects the chain from the enzymes that clear the natural hormone within minutes. No regulator anywhere has approved it as a medicine, and today it serves as a reference agonist in melanocortin receptor research.

How the peptide in Melanotan II spray works in research

Its structure is Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, a ring in which the lactam bridge holds the His-Phe-Arg-Trp motif common to every natural melanocortin in its active shape. Among the five known melanocortin receptors only MC2R is reserved for adrenocorticotropic hormone; the remaining four (MC1R, MC3R, MC4R and MC5R) are all activated by this analogue with little preference between them, and each signals through cyclic AMP. Such broad activity is exactly why receptor laboratories keep it: selective ligands are benchmarked against it, and several later selective analogues were designed from its scaffold.

Melanotan II spray research: what the published record shows

Its design paper, on potent, long-acting cyclic lactam analogues of alpha-melanotropin, appeared in 1989 in the Journal of Medicinal Chemistry. Three years later a Science paper cloned the receptor family it acts on, providing the cell systems still used to profile the compound. That cloning work matters most for day-to-day assays, because the cell lines expressing individual receptors descend from it. Peptides then published, in 2006, a history of melanocortin analogues moving from bench chemistry into clinical research. Very little of this record involves nasal delivery, so the pump bottle is best understood as a convenient ready-made solution rather than a delivery route with a body of evidence. Each paper and its design is summarised under Melanotan II research studies.

Melanotan II spray specifications

SpecificationDetail
CompoundMelanotan II nasal spray
Amount10 mg / 10 ml
FormNasal spray bottle, solution
CategoryMelanocortin research
StorageSee label

Ten milligrams of peptide are dissolved to a final volume of ten millilitres, which sets the strength at 1 mg per mL, that is 1,000 micrograms per millilitre. That round figure makes bench arithmetic simple: 0.1 mL corresponds to 100 micrograms and half a millilitre to 500 micrograms. A metered pump seals the neck, and each bottle is printed with the compound name, 10 mg total, a 10 mL fill, the 1 mg per mL strength and the lot. A 10 mL fill therefore holds a hundred 0.1 mL portions of 100 micrograms each, enough to plan several weeks of assays from a single lot. Certificates of analysis are matched to that printed lot.

Melanotan II nasal spray price in Australia

OptionPrice
Melanotan II nasal spray 10mg / 10mL$89.99

Its Australian dollar price is identical to the 10mg vial, so choosing the solution adds nothing to the cost per milligram. The difference is in handling rather than price: the solution saves buying diluent, while the vial offers longer storage.

Melanotan II spray 10mg in 10mL or the powder vial: which to buy

A made-up solution at a known 1 mg per mL removes the reconstitution step, and with it the risk of different operators preparing slightly different stocks. That suits binding and cyclic AMP assays run across a few weeks from the one bottle. Reach for the powder vial instead when reserve material has to last months in a minus 20 degree freezer, when the protocol calls for something other than 1 mg per mL, or when the peptide must go into a buffer of your own. Matching the bottle from the vial would take the full 10 mL of diluent, more than most labs want in one vial.

Best place to buy Melanotan II nasal spray in Australia

  • Sold online at macropuspeptides.com, priced at $89.99
  • Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
  • A certificate of analysis for every lot, matched to the lot number printed on the label
  • Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
  • Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
  • Payment by PayID or bank transfer, with your order ID as the reference

How to buy Melanotan II spray online

  • Place the pump bottle in your cart
  • Select a quantity that keeps your assays on one lot
  • Add the powder vial as well if long-term frozen stock is needed
  • Pay online as a research buyer aged 18 or more
  • Refrigerate the bottle on arrival and request its certificate

Storing Melanotan II nasal spray: handling a ready solution

Once a peptide is in solution, temperature and light become the main threats to its integrity, so the bottle trades the mixing step for stricter cold handling. Stand it upright in a fridge held at 2 to 8 degrees, away from light, and keep it well clear of the freezer, since ice can crack the seal and damage the peptide. Return it to the cold straight after each use rather than leaving it on the bench, and wipe and recap the pump. Note the date the bottle was first opened and the lot number in your records, and replace any bottle that has frozen or spent hours at room temperature.

Is Melanotan II spray available in Australia

Only as research material. It has no ARTG listing, the TGA has never approved it, and selling it for tanning or any therapeutic purpose, or using it on humans or animals, is not permitted. Because peptides can be rescheduled, look up the Poisons Standard entry relevant to your organisation first.

Melanotan II spray for sale Australia wide in chilled packaging

Each bottle leaves our Australian stock in chilled packaging, bound for any city or country address in any state. For melanocortin panels, compare it with PT-141 nasal spray and Melanotan 1, and see the full melanocortin research range.

References

  1. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics. Journal of Medicinal Chemistry. 1989.
  2. The cloning of a family of genes that encode the melanocortin receptors. Science. 1992.
  3. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

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Melanotan II nasal spray 10mg / 10mL$89.99