Buy Thymosin Alpha-1 Peptide in Australia
Buy Thymosin Alpha-1 in Australia from Macropus Peptides as a priced 10mg research vial. Thymosin Alpha-1 is a 28 amino acid peptide first isolated from calf thymus, known in synthetic form as thymalfasin, and it is studied in immunology for its effects on dendritic cells, Toll-like receptor signalling and T-cell maturation. Each vial holds the peptide as freeze-dried powder under a crimped seal, labelled with compound, strength, lot number and storage temperature, with a certificate of analysis for every lot. The single 10mg strength keeps a full immunology series on one batch, and 2 mL of bacteriostatic water turns it into a 5 mg per mL stock. Order Thymosin Alpha-1 online, add bacteriostatic water, and we post it from within Australia to any Australian address. For in-vitro laboratory research by adults only, not for human or veterinary use.
| Compound | Thymosin Alpha-1 |
|---|---|
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Recovery research |
| Storage | -20 °C, protect from light |
| Testing | HPLC purity 98% or higher and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
Thymosin Alpha-1 10mg vial
Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.
Buy Thymosin Alpha-1 Australia: 10mg Vial
Macropus Peptides supplies this thymic peptide in one priced strength, a 10mg vial of freeze-dried research material kept in Australia. Immunology laboratories keep it as a reference compound. Each vial comes from one source under one release process, and its printed lot code is tied to a batch certificate.
Thymosin Alpha-1 Australia: what the peptide is
It is a peptide of 28 residues, acetylated at the start of the chain and free of cysteines. Researchers purified it from thymosin fraction 5, a crude calf thymus extract, and published its isolation and sequence in the Proceedings of the National Academy of Sciences in 1977. Later work showed it is the front end of a larger nuclear protein, prothymosin alpha. The synthetic version carries the international name thymalfasin. Despite the similar name, it bears no structural relation to thymosin beta 4, the protein behind TB-500.
Its sequence runs Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN, with a molecular weight of about 3,108. Glutamate and aspartate outnumber the basic residues, so the chain carries a strong net negative charge at neutral pH, and in water it has little fixed structure until it meets a membrane-like environment.
How Thymosin Alpha-1 works in research
It does not act through one dedicated receptor. Its best described action is on the innate immune system's sensors. A 2004 study in Blood showed that it switches on mouse dendritic cells through Toll-like receptor pathways that depend on the adaptor protein MyD88, and followed how that shaped T helper 1 responses in a fungal infection model. Other cell studies link it to thymocyte maturation, cytokine release and antigen presentation. That breadth is why immunology laboratories rely on it as a reference immunomodulatory peptide rather than a selective receptor probe. Because its effects run through innate sensing machinery, experiments usually include a Toll-like receptor ligand as a positive control and cells lacking MyD88 or a given receptor to show which pathway carries the response. The acetyl group on the first residue is part of the native structure, and material lacking it is a different molecule for matching purposes, so the certificate's identity data deserve a look.
Thymosin Alpha-1 research: what the studies show
The record starts with the 1977 isolation paper. Thymosin fraction 5 was itself a mixture of many peptides, and the alpha label marks this one as among the acidic peptides separated from that extract by isoelectric focusing. In 1984 the same journal carried a description of prothymosin alpha, the larger precursor isolated from rat thymus, explaining where the peptide comes from. The 2004 Blood study then set out the dendritic cell and Toll-like receptor mechanism in mice. Most later laboratory work follows the same pattern, measuring dendritic cell activation markers, cytokine output and T-cell subsets in mouse cells and cultured immune cells. Clinical research with thymalfasin exists in several countries, but in Australia it remains a research compound. The papers, with their models and measures, are in our thymic peptide research studies library.
Thymosin Alpha-1 vial specifications
| Specification | Detail |
|---|---|
| Compound | Thymosin Alpha-1 |
| Amount | 10 mg |
| Form | Lyophilised powder |
| Category | Recovery research |
| Storage | -20 °C, protect from light |
Each vial contains a white lyophilised cake beneath a crimped closure. Printed details cover compound, strength, lot and storage temperature. Send us the lot for the batch certificate, a document worth filing with flow cytometry or cytokine data compared across months. Because the chain is acidic and flexible, it dissolves readily in water, and gentle swirling is enough to clear the cake.
Thymosin Alpha-1 price in Australia per milligram
| Strength | Price | Price per mg |
|---|---|---|
| Thymosin Alpha-1 10mg | $129.99 | $13.00 per mg |
The 10mg vial is the one size sold on its own; dividing its listed figure by ten gives the cost of each milligram. That fixed figure keeps budgeting plain: a plan that calls for 30mg across its arms needs three vials, and ordering all three together keeps them on one lot where stock allows. Set beside Thymalin, the thymic preparation in our range, the defined peptide costs more per milligram, in return for one fixed 28 residue sequence that can be matched against a reference standard.
Thymosin Alpha-1 10mg: the research vial we stock
Ten milligrams holds enough for a validation run and a confirming run on one batch. Two millilitres of water produce a 5 mg per mL thymic stock; five millilitres dilute that to 2. Expressed in molar terms, that 5 mg per mL stock is about 1.6 millimolar, a convenient anchor for molar dilution series. Split into 50 microlitre aliquots, the 2 mL stock gives forty tubes of 250 micrograms each, so a long series can draw one tube per plate without piercing the stopper again. A thousandfold dilution of one tube's contents in culture medium brings the peptide to about 1.6 micromolar, a practical top point for a dilution series.
Best place to buy Thymosin Alpha-1 Australia
- Sold online at macropuspeptides.com, priced at $129.99
- Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
- A certificate of analysis for every lot, matched to the lot number printed on the label
- Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
- Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
- Payment by PayID or bank transfer, with your order ID as the reference
How to get Thymosin Alpha-1: ordering online
- Select the 10mg vial
- Set a vial count that covers the full series
- Add a bottle of bacteriostatic water
- Confirm adult research use and pay
- Ask for the thymic peptide certificate
Thymosin Alpha-1 calculator: diluent for the 10mg vial
The calculator turns a chosen water volume into this peptide's stock strength in mg or mcg per mL. Working it through for this thymic vial, a single millilitre concentrates the peptide to 10 mg per mL, while two, four and five millilitres bring it to 5, 2.5 and 2 mg per mL in turn. For any other volume, divide ten by the millilitres added. A single 10 mL bottle of bacteriostatic water is enough to mix five vials at 2 mL each. The separate starter kit packs a 5mg vial with its own 3 mL bottle, syringes and swabs for groups that want every consumable in one carton.
Is Thymosin Alpha-1 available in Australia
As a research peptide, yes. Our thymalfasin vials hold neither ARTG registration nor TGA approval, so they are sold for bench immunology only and never for people or animals. The TGA schedules substances through the Poisons Standard, and the thymalfasin entry should be confirmed for your institution before ordering. Where thymalfasin is registered overseas it is a finished medicine; our vial is unformulated peptide for bench work.
Thymosin Alpha-1 delivery Australia wide
Orders leave our Australian base for university, institute and company laboratories nationwide, including Canberra, Hobart and Darwin. Related immune peptides include Thymalin, a thymic peptide preparation, and LL-37, the human cathelicidin, both in our recovery research range. Because the vials already sit on Australian shelves, no parcel waits on international freight or a customs check.
References
- Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide. Proceedings of the National Academy of Sciences of the USA. 1977.
- Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus. Proceedings of the National Academy of Sciences of the USA. 1984.
- Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling. Blood. 2004.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.