For laboratory research use only · Not for human or veterinary use · 18+
Metabolic research

Buy Survodutide Peptide in Australia

Lyophilised powder, 10mg vial · Available to order, dispatched from Australia
$284.99

Buy Survodutide in Australia from Macropus Peptides as a priced 10mg research vial, ready to order. Survodutide is a long-acting peptide based on the glucagon sequence and modified to add GLP-1 receptor activity, so a single molecule works at both the glucagon receptor and the GLP-1 receptor. Its glucagon arm acts mainly in the liver, which is why its published record leans toward hepatic research. The vial holds research-grade lyophilised powder under a crimped seal, labelled with compound, strength, lot number and storage temperature, and every lot has a certificate of analysis on request. Order online, add bacteriostatic water, and the order is dispatched from inside Australia to any address in the country. Survodutide is sold for in-vitro laboratory research only, to buyers aged 18 and over, and must not be used in people or animals.

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Frequently bought together
Mazdutide 10mg$294.99
For in-vitro laboratory research only. Not for human or veterinary use. Purchasers must be 18 or over.
CompoundSurvodutide
Amount10 mg
FormLyophilised powder
CategoryMetabolic research
Storage-20 °C, protect from light
TestingHPLC purity 98% or higher and mass spectrometry identity, every batch
Certificate of analysisAvailable for every lot, matched to the lot number on the label
Peptide calculator

Survodutide 10mg vial

Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.

Vial content
10 mg
mg per mL5.00
mcg per mL5,000

Buy Survodutide Australia: 10mg Research Vial

Order this glucagon and GLP-1 receptor dual agonist from Macropus Peptides in one size: a 10mg lyophilised research vial, held in Australia and priced for immediate checkout. Metabolic laboratories choose it when a study centres on the liver, since its chain starts from glucagon itself, and every vial carries a lot code that links it to its certificate of analysis.

Survodutide Australia: what the peptide is

Survodutide, coded BI 456906 during development, is a synthetic peptide derived from the sequence of glucagon, the pancreatic hormone that raises glucose output from the liver. Targeted substitutions give the chain strong activity at the GLP-1 receptor while keeping glucagon receptor activity, and they also improve its stability, since native glucagon tends to form fibrils in solution. A C18 fatty acid attached to the chain binds albumin, so the peptide circulates for days rather than minutes. It reached phase 3 clinical study, with a separate programme focused on liver disease. Its discovery paper described a deliberate imbalance: the chain is several times more potent at the GLP-1 receptor than at the glucagon receptor, a ratio chosen to add hepatic glucagon activity without letting glucose output dominate.

Survodutide peptide: how it works in liver and incretin research

Glucagon receptors are most dense on hepatocytes. Activating them increases glucose release, amino acid uptake and fatty acid oxidation in the liver, and in rodents it raises whole-body energy expenditure. The GLP-1 receptor side contributes glucose-dependent insulin release and signalling in appetite centres of the brain. Pairing the two in one molecule lets researchers study how hepatic glucagon signalling interacts with incretin signalling without a GIP component. Compared with Mazdutide, which shares the same receptor pair, this peptide differs in sequence origin, lipidation and receptor balance, so the two are often run in parallel to see which differences matter in a given assay. In primary hepatocytes the glucagon arm is followed through cyclic AMP, phosphorylation of the transcription factor CREB and expression of gluconeogenic genes such as PCK1 and G6PC, while the GLP-1 arm is usually measured in beta cell lines or receptor-transfected cells.

Survodutide research: what the published studies show

Its discovery and preclinical pharmacology were published in Molecular Metabolism in 2022, covering receptor potency at both targets and energy expenditure in rodent models. In 2024, The Lancet Diabetes and Endocrinology published a phase 2 trial comparing several exposure levels against placebo, and a phase 2 trial in metabolic dysfunction-associated steatohepatitis, published in NEJM, measured liver histology on biopsy. Phase 3 studies have since been set up for both metabolic and liver endpoints. That liver emphasis reflects where glucagon receptor activity is concentrated. Every study is described in our Survodutide research studies library.

Survodutide vial specifications

SpecificationDetail
CompoundSurvodutide
Amount10 mg
FormLyophilised powder
CategoryMetabolic research
Storage-20 °C, protect from light

The glucagon-derived peptide arrives as a compact white cake in crimp-sealed glass. Its wraparound label records name, 10mg strength, batch number and freezer temperature, and the certificate for that batch is yours on request. Store it unopened at -20 °C with no light exposure. The fatty acid side chain makes the powder slower to wet than an unlipidated peptide of similar length, so give the cake a few minutes of gentle rolling after the diluent goes in, and confirm the solution is clear and colourless before the first aliquot is drawn.

Survodutide price: one vial, one cost per mg

StrengthPricePrice per mg
Survodutide 10mg$284.99$28.50 per mg

Because only the 10mg strength is stocked, the milligram cost is simply the table figure over ten, with no size ladder to weigh up. It lands slightly under the Mazdutide vial, so a two-arm glucagon comparison stays close to even on budget. A typical hepatocyte panel that runs this peptide, Mazdutide and a GLP-1-only reference needs one vial of each dual agonist, which keeps the order small while every arm stays on a single lot.

Survodutide 10mg: the vial for liver-focused panels

One vial supports a receptor activation panel, a head-to-head arm against another dual agonist or an assay development series. Keeping a whole comparison on one batch removes a variable from the analysis. Working strengths once dissolved:

  • 1 mL: 10 mg per mL
  • 2 mL: 5 mg per mL
  • 4 mL: 2.5 mg per mL

Because glucagon-based chains can fibrillate at high concentration, many groups favour the 2 mL stock and dilute into assay buffer shortly before use. From that 5 mg per mL stock, 20 microlitres carries 100 micrograms, and a tenfold dilution in buffer gives a 500 microgram per mL working solution for the top of a hepatocyte dilution series. Discard any aliquot that turns hazy, since cloudiness in a glucagon-based solution usually signals fibril formation.

Best place to buy Survodutide Australia

  • Sold online at macropuspeptides.com, priced at $284.99
  • Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
  • A certificate of analysis for every lot, matched to the lot number printed on the label
  • Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
  • Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
  • Payment by PayID or bank transfer, with your order ID as the reference

How to get Survodutide: ordering online

  • Choose the 10mg vial and a quantity
  • Add Mazdutide or Retatrutide for comparison arms
  • Ask for bacteriostatic water on the same order
  • Pay once adult age and research use are confirmed
  • Note the batch on delivery for the certificate request

Survodutide calculator: bac water and stock strength

Enter a diluent volume into the listing's calculator and it reports the resulting strength in milligrams and micrograms per millilitre. Reference points for this vial:

  • 1 mL: 10 mg per mL
  • 2 mL: 5 mg per mL
  • 4 mL: 2.5 mg per mL

Glucagon-derived sequences are prone to fibrillation, so add bacteriostatic water slowly, roll rather than shake, and keep the solution chilled. More diluents are in lab supplies.

Is Survodutide available in Australia

It is offered purely as research material. The peptide is missing from the ARTG and holds no TGA approval of any kind, so humans and animals are off limits, and every sale is for in-vitro laboratory research. Since the Poisons Standard is updated regularly, check how it currently handles research peptides for your organisation before ordering.

Survodutide for sale Australia wide: dispatch and delivery

Orders are packed in Australia for research addresses across the mainland and Tasmania, from Perth and Darwin to Hobart, Canberra and regional university towns, each vial held upright with its seal protected. Because the stock already sits in Australia, the parcel skips international freight and customs checks. Laboratories building a glucagon comparison usually add Mazdutide and Retatrutide, and the rest of the metabolic research range is one click away.

References

  1. BI 456906: discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy. Molecular Metabolism. 2022.
  2. Glucagon and GLP-1 receptor dual agonist survodutide for obesity: a randomised, double-blind, placebo-controlled, dose-finding phase 2 trial. The Lancet Diabetes and Endocrinology. 2024.
  3. A phase 2 randomized trial of survodutide in MASH and fibrosis. New England Journal of Medicine. 2024.

Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.

Questions about Survodutide 10mg

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Survodutide 10mg$284.99