Buy HGH Fragment 176-191 Peptide in Australia
Buy HGH Fragment 176-191 in Australia from Macropus Peptides in a 5mg research vial, priced and ready to order. The peptide reproduces the last sixteen amino acids of human growth hormone, the tail region that laboratories study in fat cell and lipid metabolism models apart from the rest of the hormone. Each vial holds freeze-dried powder under a crimped seal, with a label giving compound, strength, lot number and storage temperature, and a certificate of analysis can be requested for every lot. Five milligrams keeps a full adipocyte series on one batch, and the modified tail peptide AOD-9604 is stocked beside it for side-by-side work. Add bacteriostatic water to the same parcel and it ships from our Australian shelves to any Australian address. HGH Fragment 176-191 is sold to adults aged 18 and over for in-vitro laboratory research only, never for human or veterinary use.
| Compound | HGH Fragment 176-191 |
|---|---|
| Amount | 5 mg |
| Form | Lyophilised powder |
| Category | Growth hormone research |
| Storage | -20 °C, protect from light |
| Testing | HPLC purity 98% or higher and mass spectrometry identity, every batch |
| Certificate of analysis | Available for every lot, matched to the lot number on the label |
HGH Fragment 176-191 5mg vial
Enter the diluent volume added to this vial to see the solution concentration. Laboratory calculation only, not dosing guidance.
Buy HGH Fragment 176-191 Australia: 5mg Research Vials
Macropus Peptides supplies the C-terminal fragment of human growth hormone as a priced 5mg vial of research-grade lyophilised powder, released lot by lot. It is a short synthetic peptide for laboratories that want to examine the tail end of the hormone on its own, without the growth signal carried by the rest of the molecule. The vial goes straight into the cart, and every batch has its own certificate.
HGH Fragment 176-191 Australia: what the peptide is
Human growth hormone is a protein of 191 amino acids folded into a bundle of four helices. This peptide copies positions 176 to 191, the final sixteen residues, which include two cysteines at positions 182 and 189 that close a small loop in the full hormone. Interest in that stretch began in the early 1990s, when Australian groups proposed that the end of the molecule carries its own influence on fat tissue, separate from the growth effects driven through the growth hormone receptor. At roughly 1,800 daltons, the fragment is about a twelfth the size of the intact hormone, which is why it can be made by solid-phase synthesis rather than in cells. No regulator has licensed it as a medicine, so it exists purely as a laboratory reagent.
How the HGH fragment peptide works in research
The intact hormone signals by binding two copies of the growth hormone receptor, which switches on the JAK2 and STAT5 pathway and raises IGF-1 output from the liver. Structural work shows that receptor contact is made mainly by the helices, not the tail. That is why the fragment is useful: it lets a laboratory ask what the C-terminal region does in adipocyte and lipid assays without the receptor-driven growth signal. Studies have looked at lipogenesis, the building of new fat, and lipolysis, its breakdown, in fat tissue exposed to the peptide. No dedicated receptor for the fragment has been confirmed, so its molecular target is still an open question in protocol design.
On our shelves its nearest sibling is AOD-9604, which carries this tail plus a single added tyrosine at the N-terminus. Most later animal papers used that modified form, whereas the plain fragment dominates the early lipogenesis reports, so pairing the two lets a design split the tail's own contribution from whatever the tyrosine changes. Neither raises IGF-1 in the way the whole hormone does, which keeps both at arm's length from the growth hormone axis studied with our releasing hormone analogues.
HGH fragment peptide research: what the studies show
The crystal structure of growth hormone bound to its receptor, published in Science in 1992, mapped which parts of the hormone touch the receptor and gave the structural background for studying the tail in isolation. In 1993, Biochemistry and Molecular Biology International examined how a synthetic C-terminal sequence affected lipogenesis in animal adipose tissue. Hormone Research carried metabolic studies of the modified lipolytic domain in 2000, and a study in the International Journal of Obesity in 2001 then compared the intact hormone with a modified C-terminal fragment in obese mice, measuring fat oxidation and body composition. Our fragment research studies library records each paper with its model and what it measured.
HGH fragment peptide vial specifications
| Specification | Detail |
|---|---|
| Compound | HGH Fragment 176-191 |
| Amount | 5 mg |
| Form | Lyophilised powder |
| Category | Growth hormone research |
| Storage | -20 °C, protect from light |
Inside the glass sits a small white cake of freeze-dried peptide under a rubber stopper and aluminium crimp. The label names the compound and gives its milligram content, batch code and storage temperature. Quote that batch code when you ask for the certificate of analysis and we send the document that belongs to your vial. Our storage advice for the fragment is a -20 °C freezer, in its carton, until reconstitution day, then a 2 to 8 °C fridge once water has gone in.
HGH Fragment 176-191 price: the 5mg vial in Australian dollars
| Strength | Price | Price per mg |
|---|---|---|
| HGH Fragment 176-191 5mg | $88.99 | $17.80 per mg |
The fragment is sold in one size, the 5mg vial, at a fixed Australian dollar price. Dividing that figure by five gives the cost per milligram, which is the fair basis for comparing it with AOD-9604 or with any quote from elsewhere. A single fill size also means every order draws on the same lot series, so there is no size-to-size variation to track.
HGH Fragment 176-191 5mg: the stocked vial
The 5mg vial is the size for a complete adipocyte series or a time course that should not change batch halfway through. Two millilitres of diluent produce 2.5 mg per mL, while 2.5 mL produces a round 2 mg per mL that keeps later volume sums simple. Laboratories comparing the fragment with AOD-9604 often order both in matching quantities so each arm runs at similar scale. Where a study needs more than five milligrams, ordering several vials from one dispatch keeps them on the same lot where stock allows.
Best place to buy HGH Fragment 176-191 in Australia
- Sold online at macropuspeptides.com, priced at $88.99
- Every batch HPLC tested to 98% or higher purity, with identity confirmed by mass spectrometry
- A certificate of analysis for every lot, matched to the lot number printed on the label
- Same-day dispatch from Australian stock for orders paid before 2pm AEST on a business day
- Tracked delivery Australia wide: standard in 2 to 5 working days, express in 1 to 2 working days
- Payment by PayID or bank transfer, with your order ID as the reference
How to order the HGH fragment peptide online
- Put the 5mg fragment vial in the cart and pick how many you need
- Add AOD-9604 if your design compares the two tail peptides
- Add bacteriostatic water if you do not already hold a diluent
- Pay once you have confirmed you are over 18 and buying for laboratory work
- Keep the batch code from the label for your records and the certificate
HGH fragment peptide calculator: bac water for the 5mg vial
The concentration is the milligrams in the vial divided by the millilitres of water added. Worked through for the fragment's five milligrams: 1.25 mL of water sets a 4 mg per mL concentrate; 2 mL sets 2.5 mg per mL; 2.5 mL lands on a round 2 mg per mL; and 4 mL thins it to 1.25 mg per mL, or 1,250 micrograms per millilitre. Once the vial is mixed, write the date and the chosen concentration on its label so every later draw is worked from the right figure. Bacteriostatic water in 3 mL, 10 mL and 30 mL bottles can go in the same parcel.
Is HGH Fragment 176-191 available to buy in Australia
It is available as a research chemical, which is the only form in which we sell it. Absent from the ARTG and never cleared by the TGA, the sixteen-residue tail is barred from any human or veterinary application. Peptides related to growth hormone are addressed by the Poisons Standard, which the TGA updates from time to time, so check how the current version applies to your institution before placing an order.
HGH Fragment 176-191 for sale Australia wide: onshore stock, national shipping
We ship from Australia to laboratories in Adelaide, Brisbane, Darwin, Hobart, Melbourne, Perth, Sydney, Canberra and regional campuses, with the stock already onshore. Related compounds in our growth hormone peptide range include the modified AOD-9604, IGF-1 LR3 for work further down the growth hormone axis, and releasing hormone analogues such as CJC-1295 no DAC.
References
- Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science. 1992.
- Antilipogenic action of synthetic C-terminal sequence 177-191 of human growth hormone. Biochemistry and Molecular Biology International. 1993.
- Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Hormone Research. 2000.
- Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. International Journal of Obesity. 2001.
Scientific content compiled from the peer-reviewed literature above by the Macropus Peptides technical team. Information is provided for research reference only.